Efficacy of pharmacological methods used for treating tobacco dependence: meta-analysis

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Efficacy of pharmacological methods used for treating tobacco dependence: meta-analysis.

OBJECTIVES The present study summarizes available evidence describing efficacy of pharmacological methods used in smoking cessation and presents the results of new meta-analyses examining their 12-month efficacy. This work represents part of a larger program examining the efficacy and cost-effectiveness of different methods used in smoking cessation. PATIENTS AND METHODS The first part of the...

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Tobacco use continues to cause 5 million preventable deaths worldwide each year. Despite effective treatments being available, these are underutilized and cessation rates remain low. As tobacco use has complex physiological effects, there are multiple opportunities for novel pharmacological agents to play a role in a comprehensive treatment plan. The endocannabinoid system has been linked to th...

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Treating tobacco dependence

Most cigarettes contain around 10 mg of nicotine, about 1 mg of which is actually absorbed by inhalation of smoke. An average smoker awakens in the morning with blood nicotine levels of less than 5 ng/ml (the half-life of nicotine is about two hours). Afternoon nicotine levels are generally in the range of 15-80 ng/ml. The typical nicotine boost from an afternoon cigarette is 10-15 ng/ml (Fould...

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ژورنال

عنوان ژورنال: Polish Archives of Internal Medicine

سال: 2008

ISSN: 1897-9483

DOI: 10.20452/pamw.296